![](https://agnopharma.com/wp-content/uploads/2024/08/oral-solid.jpeg)
Multiple solubility and bioavailability enhancement techniques
We utilize multiple formulation techniques to increase the bioavailability of poorly soluble APIs for oral drug delivery. Our team will explore different approaches for your product until we find the solution that meets your needs, including:
- Amorphous solid dispersions (ASDs)
- Hot melt extrusion (HME)
- Spray drying
- Nano- and microparticle technologies
- Nanomilling
- API encapsulation
- Multi-particulate systems
- Fluid bed coating, granulation, and drying
- Complexation
Analytical capabilities and ICH stability
All formulation development and optimization for oral drug delivery is supported by our analytical services team, which works closely with formulators on method development and validation as projects progress from R&D to GMP production. In-house characterization of complex oral solid dosage forms includes drug assay and related substances, encapsulation efficiency, in vitro dissolution testing, Karl Fisher moisture analysis, particle size distribution analysis, and more.
We also offer on-site design and execution of ICH stability programs. Our facility is equipped with state-of-the-art temperature and humidity controlled and monitored chambers for accelerated and long-term stability testing. Agno Pharma is prepared to be your partner from early-stage development through stability and release testing.
We keep the end formulation goal at the center of what we do and adapt our methods accordingly.
![](https://agnopharma.com/wp-content/uploads/2024/08/oral.jpeg)